This issue of Surgical Oncology Clinics, guest edited by Dr. Bridget N. Fahy, is devoted to Palliative Care in Surgical Oncology. Dr. Fahy has assembled expert authors to review the following topics: Current guidelines for integration of palliative care in oncology; Management of malignant bowel obstruction; Management of peritoneal carcinomatosis & malignant ascites; Artificial nutrition in patients with advanced malignancy; Selecting patients for palliative procedures in oncology; Palliative radiotherapy: Indications and outcomes; Ethical considerations for caring for patients with advanced cancer; Evaluation and management of malignant biliary obstruction; Systemic anti-cancer treatments for advanced cancer patients: What a surgical oncologist needs to know; Role of palliative medicine training in surgical oncology; Navigating difficult conversations: Breaking bad news and exploring goals of care in surgical patients; Strategies for optimizing perioperative pain management for the cancer patient; and more!